Plasma folate, vitamin B-6, vitamin B-12, and risk of breast cancer in women
نویسندگان
چکیده
منابع مشابه
Folate, vitamin B(6), and vitamin B(12) intake and the risk of breast cancer among Mexican women.
BACKGROUND High intake of folate, vitamin B(6), and vitamin B(12) have been hypothesized to lower the risk for breast cancer. We conducted a population-based case-control study to evaluate the risk for breast cancer among Mexican women with relatively low vitamin intakes. METHODS We included 475 women (median age, 53 years; range, 23-87 years) diagnosed with incident breast cancer through six...
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BACKGROUND B vitamins [vitamins B-6, B-9 (folate), and B-12] play important roles in nucleotide biosynthesis and biological methylation reactions, aberrancies of which have all been implicated in carcinogenesis. In the general population, evidence has suggested that high circulating folate and folic acid (synthetic form of folate) supplement use may increase breast cancer risk, but the role of ...
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Serum homocysteine concentrations have been shown to be a sensitive functional indicator of intracellular folate, vitamin B-12, and vitamin B-6 status. Chronic alcoholism is known to interfere with one-carbon metabolism, for which the above vitamins serve as coenzymes. In the present study, these vitamins were assessed in 32 chronic alcoholics and 31 healthy volunteers by measuring blood vitami...
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BACKGROUND Folate, vitamin B-12, and vitamin B-6 are essential nutritional components in one-carbon metabolism and are required for methylation capacity. The availability of these vitamins may therefore modify methylation of phosphatidylethanolamine (PE) to phosphatidylcholine (PC) by PE-N-methyltransferase (PEMT) in the liver. It has been suggested that PC synthesis by PEMT plays an important ...
متن کاملFolate and Vitamin B
Forty-one patients with oral lesions and symptoms were enrolled in the study. Their ages ranged from 16 to 79 years with a mean age of 48.5 years. They were divided into two groups. Group I consisted of 25 patients with oral lichen planus and group II consisted of 16 patients with stomatitis or glossitis. Their complete blood counts, hemoglobin typing, serum and red cell folate, and serum vitam...
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ژورنال
عنوان ژورنال: The American Journal of Clinical Nutrition
سال: 2008
ISSN: 0002-9165,1938-3207
DOI: 10.1093/ajcn/87.3.734